Crystal Structure of 7-((7S)-7-Amino-5-azaspiro(2.4)heptan-5-yl)-8-chloro-6-fluoro-1-((1R,2S)-2-fluoro-1-cyclopropyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid.
نویسندگان
چکیده
منابع مشابه
Crystal structure of 1-cyclopropyl-2-ethyl-5-fluoro-6- (4-methylpiperazin-1-yl)-1H-benzimidazole.
biological activities,1 and some of them are used as drugs.2,3 In previous studies,4,5 we reported on the synthesis and biological evaluation of 1,2,5(6)-trisubstituted benzimidazoles as antihistaminic and antimicrobial agents. The synthesis of ethyl 1-cyclopropyl-5-fluoro-6-(4-methylpiperazine-1-yl)-1H-benzimidazole-2-acetate (1) was performed according to reported methods.6,7 1-Cyclopropyl-2-...
متن کامل1-Cyclopropyl-6-fluoro-7-(4-nitrosopiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
The title compound, C(17)H(17)FN(4)O(4), is a derivative of ciprofloxacin [1-cyclo-propyl-6-fluoro-4-oxo-7-(1-piperazin-yl)-1,4-dihydro-quinoline-3-carboxylic acid]. The crystal packing is stabilized by inter-molecular C-H⋯O hydrogen bonds together with π-π electron ring inter-actions [centroid-centroid separations between quinoline rings of 3.5864 (11) and 3.9339 (13) Å]. A strong intra-molecu...
متن کاملEthyl 7-chloro-1-cyclopropyl-6-fluoro-8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylate
In the title compound, C(15)H(12)ClFN(2)O(5), mol-ecules are packed in the crystal lattice in a parallel fashion sustained by various C-H⋯O [C⋯O = 3.065 (5)-3.537 (5) Å] and C-H⋯Cl [3.431 (5)-3.735 (4) Å] inter-actions.
متن کامل4-(3-Carboxy-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-7-quinolyl)-1-methylpiperazinium picrate
The pefloxacinium cation of the title salt, C(17)H(21)FN(3)O(3) (+)·C(6)H(2)N(3)O(7) (-), is composed of an essentially planar quinoline ring system [maximum deviation = 0.021 (2) Å] and a piperazine ring, which adopts a chair conformation. In the picrate anion, the two O atoms of one of the o-NO(2) groups are disordered over two positions, with an occupancy ratio of 0.56 (4):0.44 (4). In the c...
متن کامل6-Chloro-7-fluoro-4-oxo-4H-chromene-3-carbaldehyde
In the title compound, C10H4ClFO3, a chlorinated and fluorinated 3-formyl-chromone derivative, all atoms are essentially coplanar (r.m.s. = 0.0336 Å for the non-H atoms), with the largest deviation from the least-squares plane [0.062 (2) Å] being for a benzene-ring C atom. In the crystal, mol-ecules are linked through stacking inter-actions [centroid-centroid distance between the benzene and py...
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ژورنال
عنوان ژورنال: Analytical Sciences
سال: 1998
ISSN: 0910-6340,1348-2246
DOI: 10.2116/analsci.14.463